In Ecuador, men who have sex with men (MSM) are disproportionally affected by HIV. HIV prevalence is also higher among transgender people. This is because discrimination often leads to people being denied access to health services and information.

The Alliance has been working on HIV in Ecuador with Corporación Kimirina since 1999 to improve access to HIV and health services. Kimirina, along with the other community organisations it supports in Ecuador, aims to mobilise sex workers, people living with HIV, transgender people and men who have sex with men, so that they are able to advocate for their rights to health services, and to access health information and services.

Kimirina also provides direct services; in 2016 they reached over 54,000 marginalised people with programmes to prevent HIV in Ecuador. They are also producing innovative online resources, such as the digital prevention platform ponteonce.org, a website for men who have sex with men. Corporación Kimirina are a principal recipient of the Global Fund and will continue to work on HIV prevention services in Ecuador.